SMC2 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residues 50 and 100 of human Structural Maintenance of Chromosomes 2 using the numbering given in entry NP_006435.1 (GeneID 10592).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
SMC2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
NB 100-371 may be used for Western Blot, where a band at ~155 kDa is seen, representing SMC2 protein. Suggested working dilutions: * Western Blot – 1:5,000-1:20,000 Immunocytochemistry – Not Tested Immunoprecipitation – Not Tested *The investigator should determine the optimal working dilution for a specific application.
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| Publications |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for SMC2 Antibody
- CAP-E
- CAPESMC2 structural maintenance of chromosomes 2-like 1 (yeast)
- Chromosome-associated protein E
- FLJ10093
- hCAP-EXCAP-E homolog
- SMC protein 2
- SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
- SMC2 structural maintenance of chromosomes 2-like 1
- SMC-2
- SMC2L1
- structural maintenance of chromosomes (SMC) family member
- structural maintenance of chromosomes 2
- structural maintenance of chromosomes protein 2
Background
Structural Maintenance of Chromosome (SMC) proteins are required for nuclear processes, including chromosome condensation, chromatid cohesion, and DNA repair. Eukaryotic proteins are capable of binding DNA and possess a DNA-stimulated ATPase activity.