SMARCAD1 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 976 and 1026 of human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (enhancer trap locus 1) using the numbering given in entry NP_064544.1 (GeneID 56916).
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| Predicted Species |
Mouse (100%), Rat (100%), Porcine (100%), Primate (100%), Bovine (100%), Equine (100%), Guinea Pig (100%), Rabbit (100%), Canine (100%), Monkey (100%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
SMARCAD1
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Positive Control |
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Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Whitetufted-ear marmoset, Crab-eating macaque, European domestic ferret and Northern white-cheeked gibbon.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
TBS and 0.1% BSA
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| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for SMARCAD1 Antibody
- ATP-dependent helicase 1
- DKFZP762K2015
- EC 3.6.1
- EC 3.6.4.12
- HEL1
- hHEL1
- KIAA1122ETL1DKFZp762K2015
- subfamily a, containing DEAD/H box 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A containing DEAD/H box 1
- SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin
Background
The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAD1/ETL1 is a unique member of this family in that it contains two DEAD/H box motifs, and thus is also a member of the DEAD/H-box-containing helicase superfamily. The chromosomal position of SMARCAD1 has been mapped, and it resides in a region rich in breakpoints and deletions associated with several human diseases. It is suggested to play a role in genetic instability and development.