SHPRH Antibody

Product: 20-O-Acetylingenol-5-angelate

SHPRH Antibody Summary

Immunogen
Residues 515-535 (DKTKKQAVGSPRKIEKELRKS) of the mouse SHPRH protein. 95% sequence identity to rat. 90% sequence identity to human.
Specificity
This is specific for SHPRH.
Clonality
Polyclonal
Host
Rabbit
Gene
SHPRH
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This antibody may be used for Western blot. No other assays have been tested. Suggested working dilutions: * Western Blot – 1:250 ~ 1:500 *The investigator should determine the optimal working dilution for a specific application.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Theoretical MW
180 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SHPRH Antibody

  • 2610103K11Rik
  • bA545I5.2
  • E3 ubiquitin-protein ligase SHPRH
  • EC 3.6.4.-
  • EC 6.3.2.-
  • FLJ27258
  • FLJ37625
  • FLJ90837
  • histone-linker, PHD and RING finger domain-containing helicase
  • KIAA2023FLJ45012
  • MGC134886
  • SNF2 histone linker PHD RING helicase

Background

A novel gene containing SNF2, PHD-finger, RING-finger, helicase, and linker histone domains termed SHPRH, is a possible candidate for a tumor suppressor gene. These domains are characteristic of several DNA repair proteins, transcription factors, and helicases. Mapping of this gene to 6q24, a region reported to contain a tumor suppressor locus suggests a role in tumor suppression.

PMID: 17392452