SF3B4 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SF3B4. The exact sequence is proprietary.
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| Localization |
Nucleus
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
SF3B4
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Xenopus laevis (100%), Xenopus tropicalis (100%), Rhesus Monkey (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
|
Alternate Names for SF3B4 Antibody
- Hsh49
- pre-mRNA splicing factor SF3b 49 kDa subunit
- Pre-mRNA-splicing factor SF3b 49 kDa subunit
- SAP 49
- SAP49MGC10828
- SF3b49
- SF3b50
- spliceosomal protein
- spliceosome-associated protein (U2 snRNP)
- Spliceosome-associated protein 49
- splicing factor 3B subunit 4
- splicing factor 3b, subunit 4, 49kD
- splicing factor 3b, subunit 4, 49kDa
Background
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq]