SEC6 Antibody (4A7) Summary
| Immunogen |
EXOC3 (NP_009208, 646 a.a. ~ 746 a.a) partial recombinant protein with GST tag.SGFGEDVDGYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPAQASPSYVPLFKDIVVPSLNVAKLLK
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| Specificity |
EXOC3 (4A7)
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| Isotype |
IgG2b Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
EXOC3
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| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against transfected lysate and recombinant protein for western blot. It has also been used for ELISA.
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| Publications |
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Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
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| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SEC6 Antibody (4A7)
- exocyst complex component 3
- Exocyst complex component Sec6
- Sec 6 homolog
- SEC6
- SEC6L1
- SEC6-like 1 (S. cerevisiae)
- SEC6-like 1
- Sec6p
Background
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.