S1P5/EDG-8 Antibody

Product: Apoptosis Activator 3

S1P5/EDG-8 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human S1PR5 / EDG8.
Epitope
N-terminal extracellular domain of human
Specificity
Sphingolipid Receptor Edg8
Predicted Species
Mouse (94%), Bovine (94%), Primate (100%), Hamster (94%), Canine (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
S1PR5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 3 ug/ml
Publications
Read Publications using NLS3802.

Reactivity Notes

Gorilla, Marmoset, Elephant (100%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for S1P5/EDG-8 Antibody

  • EDG8
  • Edg-8
  • EDG8S1P receptor Edg-8
  • Endothelial differentiation G-protein-coupled receptor 8
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
  • LPB4
  • S1P receptor 5
  • S1P5
  • S1PR5
  • sphingosine 1-phosphate receptor 5
  • sphingosine 1-phosphate receptor EDG8
  • Sphingosine 1-phosphate receptor Edg-8
  • sphingosine-1-phosphate receptor 5
  • SPPR-1
  • SPPR-2

Background

Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. Caution: The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1.

PMID: 15324884

S1P5/EDG-8 Antibody

Product: CWHM-13

S1P5/EDG-8 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from 2nd cytoplasmic domain of human S1PR5 / EDG8.
Epitope
Cytoplasmic Domain
Specificity
Sphingolipid Receptor Edg8
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
S1PR5
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 4 ug/ml
Publications
Read Publication using
NLS316 in the following applications:

  • WB
    1 publication

Reactivity Notes

Gorilla (100%); Marmoset (89%); Mouse, Rat, Hamster, Dog, Bat (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for S1P5/EDG-8 Antibody

  • EDG8
  • Edg-8
  • EDG8S1P receptor Edg-8
  • Endothelial differentiation G-protein-coupled receptor 8
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
  • LPB4
  • S1P receptor 5
  • S1P5
  • S1PR5
  • sphingosine 1-phosphate receptor 5
  • sphingosine 1-phosphate receptor EDG8
  • Sphingosine 1-phosphate receptor Edg-8
  • sphingosine-1-phosphate receptor 5
  • SPPR-1
  • SPPR-2

Background

Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. Caution: The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1.

PMID: 16610793