Product: Apoptosis Activator 3
S1P5/EDG-8 Antibody Summary
| Immunogen |
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human S1PR5 / EDG8.
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| Epitope |
N-terminal extracellular domain of human
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| Specificity |
Sphingolipid Receptor Edg8
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| Predicted Species |
Mouse (94%), Bovine (94%), Primate (100%), Hamster (94%), Canine (94%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
S1PR5
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| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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| Publications |
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Reactivity Notes
Gorilla, Marmoset, Elephant (100%)
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for S1P5/EDG-8 Antibody
- EDG8
- Edg-8
- EDG8S1P receptor Edg-8
- Endothelial differentiation G-protein-coupled receptor 8
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
- LPB4
- S1P receptor 5
- S1P5
- S1PR5
- sphingosine 1-phosphate receptor 5
- sphingosine 1-phosphate receptor EDG8
- Sphingosine 1-phosphate receptor Edg-8
- sphingosine-1-phosphate receptor 5
- SPPR-1
- SPPR-2
Background
Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. Caution: The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1.