Product: GSK2110184 (hydrochloride)
S1P3/EDG-3 Antibody Summary
| Immunogen |
Synthetic 18 amino acid peptide from C-terminus of human EDG3 / S1P3.
|
| Specificity |
Human EDG3 / S1P3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TPRX1 (56%).
|
| Predicted Species |
Monkey (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
S1PR3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (94%), Elephant (94%), Bovine (89%), Gibbon (83%), Rabbit (83%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for S1P3/EDG-3 Antibody
- EDG3
- EDG-3
- EDG3FLJ37523
- Endothelial differentiation G-protein coupled receptor 3
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
- FLJ93220
- G protein-coupled receptor, endothelial differentiation gene-3
- LPB3
- MGC71696
- S1P receptor 3
- S1P receptor EDG3
- S1P receptor Edg-3
- S1P3
- S1PR3
- sphingosine 1-phosphate receptor 3
- Sphingosine 1-phosphate receptor Edg-3
- sphingosine-1-phosphate receptor 3
Background
EDG3, a Lysophospholipid/Lysosphingolipid Receptor, binds the vasoconstrictor sphingosine-1-phosphate and activates transcription of serum response element-driven reporter genes. EDG3 may regulate angiogenesis and vascular endothelial cell functions. EDG3 has been reported in all tissues, with highest levels in heart, placenta, kidney, and liver. ESTs have been isolated from placenta and germ cell tumor libraries.