Product: Benzenepentacarboxylic Acid
RanBP2 Antibody Summary
| Immunogen |
Synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2.
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| Localization |
Nuclear
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
RANBP2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
PBS containing 1 mg/ml BSA
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| Preservative |
0.05% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for RanBP2 Antibody
- ANE1
- E3 SUMO-protein ligase RanBP2
- EC 5.2.1.8
- Nuclear pore complex protein Nup358
- nucleoporin 358
- Nucleoporin Nup358
- NUP358TRP2
- p270
- RAN binding protein 2
- Ran-binding protein 2
- RanBP2
- transformation-related protein 2,358 kDa nucleoporin
- TRP1
Background
Transport of macromolecules into and out of the nucleus occurs through nuclear pore complexes (NPC). This energy-dependent process involves nucleoporins at the NPC, associated transport proteins and GTP. The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane.