Rad51C Antibody

Product: LY2940680

Rad51C Antibody Summary

Immunogen
Peptide with sequence RGKTFRFEMQRDL-C corresponding to N-Terminus according to NP_002867.1, NP_478123.1.
Specificity
This antibody is expected to recognise all reported human isoforms.
Clonality
Polyclonal
Host
Goat
Gene
RAD51C
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1 – 3 ug/ml
  • Immunohistochemistry-Paraffin 1:10 – 1:500
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 45 kDa band observed in HeLa lysate (predicted MW of 41 kDa band according to NP_478123).
Positive Control
HeLa Lysate (NB800-PC1)
Publications
Read Publication using NB100-1127.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Rad51C Antibody

  • BROVCA3
  • DNA repair protein RAD51 homolog 3
  • FANCO
  • MGC104277
  • R51H3
  • RAD51 homolog C (S. cerevisiae)
  • RAD51 homolog C
  • RAD51L2RAD51 (S. cerevisiae) homolog C
  • RAD51-like protein 2
  • yeast RAD51 homolog 3

Background

The Rad51 DNA repair protein is a key component of the double-strand break repair pathway and is essential for mitotic and meiotic recombination and genome stability. Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes.

PMID: 20060592