RHBDD2 Antibody

Product: Ranirestat

RHBDD2 Antibody Summary

Immunogen
Antibody was raised against an 18 amino acid synthetic peptide from near the center of human RHBDD2. The immunogen is located within amino acids 220 – 270 of RHBDD2.
Clonality
Polyclonal
Host
Rabbit
Gene
RHBDD2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunocytochemistry 20 ug/ml
Control Peptide
RHBDD2 Peptide (NBP1-76249PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RHBDD2 Antibody

  • H_RG122E10.2a
  • H_RG122E10.2b
  • rhomboid domain containing 2
  • rhomboid domain-containing protein 2
  • rhomboid, veinlet-like 7
  • veinlet-like 7 (Drosophila)

Background

The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. Little is known about the role of RHBDD2. Its overexpression in breast carcinoma appears to be an indicator of poor prognosis and may play a role in breast cancer progression. The related proteins RHBDD1 and RHBDD3 are both involved in the regulation of apoptosis, suggesting that RHBDD2 may also be involved in the modulation of apoptotic activity.

PMID: 20979137