RDH5 Antibody

Product: Tetrabenazine ((+)-)

RDH5 Antibody Summary

Immunogen
Peptide with sequence C-RDRQSLPASNAFV corresponding to internal region according to NP_002896.2.
Epitope
C-RDRQSLPASNAFV
Clonality
Polyclonal
Host
Goat
Gene
RDH5
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 2 – 4 ug/ml
  • Immunohistochemistry 5 – 10 ug/ml
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Approx. 35 kDa band observed in mouse eye lysates (calculated MW of 34.8 kDa band according to mouse NP_598767.1). IHC-P: Human Retina shows staining of the ganglion cell layer.
Publications
Read Publication using NBP1-52047.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for RDH5 Antibody

  • 11-cis RDH
  • 11-cis retinol dehydrogenase
  • 9,9-cis-retinol specific dehydrogenase
  • EC 1.1.1
  • EC 1.1.1.105
  • FLJ39337
  • FLJ97089
  • HSD17B
  • RDH1
  • retinol dehydrogenase 1
  • retinol dehydrogenase 5 (11-cis and 9-cis)
  • retinol dehydrogenase 5 (11-cis/9-cis)
  • SDR9C5
  • short chain dehydrogenase/reductase family 9C, member 5

Background

This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. [provided by RefSeq]

PMID: 11250866