RAD18 Antibody (2B9) Summary
| Immunogen |
RAD18 (NP_064550, 332 a.a. ~ 431 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.EKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEV
|
| Specificity |
RAD18 – RAD18 homolog (S. cerevisiae) (2B9)
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
RAD18
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
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Reactivity Notes
Human, Rat.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for RAD18 Antibody (2B9)
- EC 6.3.2.-
- hHR18
- hRAD18
- postreplication repair protein hRAD18p
- Postreplication repair protein RAD18
- RAD18 homolog (S. cerevisiae)
- RAD18, S. cerevisiae, homolog
- RING finger protein 73
- RNF73E3 ubiquitin-protein ligase RAD18
Background
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]