Product: L-Ascorbic acid (sodium)
RAB10 Antibody (4E2) Summary
| Immunogen |
Purified recombinant fragment of human Rab10 expressed in E. Coli.
|
| Isotype |
IgG1
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
RAB10
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
22.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
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Alternate Names for RAB10 Antibody (4E2)
- GTP-binding protein RAB10
- RAB10, member RAS oncogene family
- ras-related GTP-binding protein
- ras-related protein Rab-10
Background
RAB10, member RAS oncogene family. The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.