QBRICK/FREM1 Antibody Summary
| Immunogen |
Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FREM1. The immunogen is located within the last 50 amino acids of FREM1.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
FREM1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for QBRICK/FREM1 Antibody
- BNAR
- C9orf143chromosome 9 open reading frame 154
- C9orf145C9orf154extracellular matrix protein QBRICK
- C9orf154
- DKFZp686M16108
- FLJ25461
- FRAS1 related extracellular matrix 1
- FRAS1-related extracellular matrix protein 1
- FREM1
- Protein QBRICK
- QBRICK
- TILRR
Background
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.