Product: Tarafenacin (D-tartrate)
Prolactin R Antibody (B6.2) [Alexa Fluor® 488] Summary
| Immunogen |
Semi-purified human prolactin receptor
|
| Localization |
Cell surface and cytoplasmic
|
| Specificity |
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PRLR
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Immunohistochemistry (Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.)
|
| Theoretical MW |
70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A purified
|
Alternate Names for Prolactin R Antibody (B6.2) [Alexa Fluor® 488]
- delta 4-delta 7/11 truncated prolactin receptor
- delta 4-SF1b truncated prolactin receptor
- hPRL receptor
- hPRLrI
- PRLR
- PRL-R
- Prolactin R
- prolactin receptor delta 7/11
- prolactin receptor
- ProlactinR
- secreted prolactin binding protein