Presenilin-1 Antibody

Product: CFMTI

Presenilin-1 Antibody Summary

Immunogen
Synthetic peptides corresponding to the N terminal sequence MVELMFP and the C terminal sequence LLGLPID of the human Presenilin 1 protein.
Specificity
Reacts with N terminal sequence MVELMFP and the C terminal sequence LLGLPID of the human Presenilin 1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
PSEN1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
This Presenilin 1 antibody is useful for Immunoprecipitation, Immunohistochemistry frozen and paraffin embedded sections and ELISA.
Positive Control
Presenilin-1 Lysate (NBL1-14860)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Presenilin-1 Antibody

  • AD3EC 3.4.23.-
  • Alzheimer disease 3
  • EC 3.4.23
  • FAD
  • presenilin 1
  • Presenilin1
  • Presenilin-1
  • Protein S182
  • PS-1
  • PS1presenilin-1
  • PSEN1
  • PSNL1
  • S182

Background

Presenilin 1 is a novel prostate short-chain dehydrogenase/reductase that exhibits increased expression on exposure to androgens in the LNCaP prostate cancer cell line. Presenilin 1 is expressed in normal and neoplastic prostate epithelium and is implicated in the pathogenesis of prostate carcinoma.

PMID: 15078799