Product: Pamidronate (disodium pentahydrate)
Phosphodiesterase 4A/PDE4A [p Ser686, p Ser688] Antibody Summary
Immunogen |
Synthetic peptide corresponding to PKA phosphorylation site on PDE4A long form enzymes. The peptide was synthesized with phosphorylated serine.
|
Modification |
p Ser686, p Ser688
|
Localization |
Cell Membrane
|
Specificity |
This detects all known long-from variants of PDE4A, including PDE4A4, PDE4A5, PDE4A8, PDE4Ax when phosphorylated at the PKA phophorylation site. It will not cross-react with PDE4A phosphorylated at the ERK phosphorylation site. It does not cross-react with PDE4B, PDE4D or any other member of the PDE family.
|
Clonality |
Polyclonal
|
Host |
Rabbit
|
Gene |
PDE4A
|
Purity |
Immunogen affinity purified
|
Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
Dilutions |
|
||
Application Notes |
Immunoprecipitation and Western Blot: Detects bands at 66 kDa (PDE4A1), 109 kDa (PDE4A5), 106 kDa(PDE4A8), 102 kDa (PDE4Ax) and 76 kDa (testis specific PDE4A variant). Optimal dilutions and concentrations should be determined by the end user.
|
||
Positive Control |
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
Buffer |
Tris/Glycine buffer pH 7.5-7.9, stabilizing protein, and glycerol
|
Preservative |
0.02% Sodium Azide
|
Purity |
Immunogen affinity purified
|
Alternate Names for Phosphodiesterase 4A/PDE4A [p Ser686, p Ser688] Antibody
- cAMP-specific 3-5-cyclic phosphodiesterase 4A
- DPDE2
- DPDE2cAMP-specific phosphodiesterase
- EC 3.1.4
- EC 3.1.4.17
- PDE4
- PDE46
- PDE4A
- Phosphodiesterase 4A
- phosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homologphosphodiesterase E2)
- phosphodiesterase 4A, cAMP-specific (dunce
- phosphodiesterase 4A, cAMP-specific
- phosphodiesterase E2 dunce homolog, Drosophila
- phosphodiesterase isozyme 4