Perforin Antibody Summary
| Immunogen |
Synthetic peptide surrounding amino acid 568 of rat Perforin (NP_059026).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PRF1
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects ~70 kDa Perforin in samples from human, mouse and rat origins. Reactivity to other species has not been determined.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2), 0.5% BSA and 30% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.5 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Perforin Antibody
- Cytolysin
- FLH2
- HPLH2
- HPLH2lymphocyte pore forming protein
- Lymphocyte pore-forming protein
- MGC65093
- P1PFN1
- perforin 1 (pore forming protein)
- perforin-1
- PFPcytolysin
Background
This antibody clone reacts with human perforin (pore-forming protein, pfp). Perforin is one of the cytolytic mediators present in the cytoplasmic granules of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Perforin is involved in the killing function by CTLs and NKs and has an important role in the immune response against tumors and virus infections.