PPIG Antibody

Product: IDO-IN-3

PPIG Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 375 and 325 of human SR-cyclophilin (Peptidyl-prolyl isomerase G) using the numbering given in entry NP_004783.2 (GeneID 9360).
Clonality
Polyclonal
Host
Rabbit
Gene
PPIG
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry
  • Immunoprecipitation 2-5 ug/mg lysate

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PPIG Antibody

  • CARS-cyclophilin
  • CARS-CypPPIase G
  • CASP10
  • Clk-associating RS-cyclophilin
  • Cyclophilin G
  • CYP
  • EC 5.2.1.8
  • MGC133241
  • peptidyl-prolyl cis-trans isomerase G
  • peptidylprolyl isomerase G (cyclophilin G)
  • peptidyl-prolyl isomerase G (cyclophilin G)
  • Peptidyl-prolyl isomerase G
  • Rotamase G
  • SCAF10
  • SR-cyclophilin
  • SRCyp
  • SR-cyp
  • SR-related CTD-associated factor 10

Background

SR cyclophilin (SRcyp) is also known as peptidyl-prolyl cis-trans isomerase G. Cyclophilins are peptidyl-prolyl isomerases (PPIases) that accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. The function of cyclophilins is poorly understood, but their function has been linked to multiple cellular processes such as protein folding, trafficking, and chaperone activity. SRcyp is a member of the Moca family of nuclear cyclophilins and is phosphorylated in a cell cycle dependent manner. There is evidence that SRcyp may be involved in the regulation of gene expression and mRNA splicing. Alternative names for SRcyp include PPIase G, rotamase G, cyclophilin G, clk-associating RS-cyclophilin, CARS-cyclophilin, SR-cyp, CASP10, and PPIG.

PMID: 12182954