PPAPDC3 Antibody Summary
| Immunogen |
Antibody was raised against a 19 amino acid synthetic peptide from near the amino of terminus human PPAPDC3. The immunogen is located within the first 50 amino acids of PPAPDC3.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
PPAPDC3
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for PPAPDC3 Antibody
- C9orf67
- chromosome 9 open reading frame 67
- EC 3.1.3
- EC 3.1.3.-
- FLJ14662
- KIAA0515
- MGC12921
- NET39
- phosphatidic acid phosphatase type 2 domain containing 3
- Phosphatidic acid phosphatase type 2 domain-containing protein 3
- probable lipid phosphate phosphatase PPAPDC3
Background
PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.