PIK3C2A Antibody (3E7.) Summary
| Immunogen |
PIK3C2A (NP_002636 1577 a.a. – 1686 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLTAATYL
|
| Specificity |
PIK3C2A – phosphoinositide-3-kinase, class 2, alpha polypeptide (3E7)
|
| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
PIK3C2A
|
| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PIK3C2A Antibody (3E7.)
- C2-containing phosphatidylinositol kinase
- CPK
- DKFZp686L193
- EC 2.7.1
- EC 2.7.1.154
- MGC142218
- phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha
- Phosphoinositide 3-kinase-C2-alpha
- phosphoinositide-3-kinase, class 2, alpha polypeptide
- PI3-K-C2(ALPHA)
- PI3-K-C2A
- PI3K-C2alpha
- PI3K-C2-alpha
- PtdIns-3-kinase C2 subunit alpha
Background
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq]