Product: Oxidopamine (hydrochloride)
PIAS1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the N-terminus region of human PIAS1. The exact sequence is proprietary.
|
| Localization |
Nucleus speckle
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PIAS1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
72 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rhesus Monkey (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.64 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PIAS1 Antibody
- AR interacting protein
- DDXBP1MGC141878
- DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
- DEAD/H box-binding protein 1
- E3 SUMO-protein ligase PIAS1
- GBPRNA helicase II-binding protein
- GU/RH-II
- Gu-binding protein
- MGC141879
- Protein inhibitor of activated STAT protein 1
- protein inhibitor of activated STAT, 1
- protein inhibitor of activated STAT-1
- zinc finger, MIZ-type containing 3
- ZMIZ3
Background
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq]