Product: (1S,3R,5R)-PIM449 (dihydrochloride)
PEG10 Antibody Summary
| Immunogen |
PEG10 (NP_001035242.1, 1 a.a. ~ 325 a.a) full-length human protein.
|
| Clonality |
Polyclonal
|
| Host |
Mouse
|
| Gene |
PEG10
|
| Purity |
Protein G purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is useful for Western Blot, Immunofluorescence
|
Reactivity Notes
This product is reactive against Human.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein G purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PEG10 Antibody
- embryonal carcinoma differentiation regulated
- Embryonal carcinoma differentiation-regulated protein
- HB-1
- KIAA1051EDR
- Mammalian retrotransposon-derived protein 2
- Mar2
- Mart2
- MEF3 like 1
- MEF3L
- MEF3L1
- Myelin expression factor 3-like protein 1
- paternally expressed 10
- Paternally expressed gene 10 protein
- retrotransposon gag domain containing 3
- Retrotransposon gag domain-containing protein 3
- Retrotransposon-derived gag-like polyprotein
- retrotransposon-derived protein PEG10
- RGAG3MEF3-like protein 1
- Ty3/Gypsy-like protein
Background
This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frame shifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.