PDK4 Blocking Peptide Summary
| Protein/Peptide Type |
Blocking Peptide
|
| Gene |
PDK4
|
Applications/Dilutions
| Application Notes |
This peptide is useful as a blocking peptide for NBP1-07049.For further blocking peptide related protocol, click here.
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
Peptide dissolved in dH2O. Contains no BSA.
|
| Preservative |
No Preservative
|
| Concentration |
1.0 mg/ml
|
Alternate Names for PDK4 Blocking Peptide
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial
- EC 2.7.11
- EC 2.7.11.2
- FLJ40832
- Pyruvate dehydrogenase kinase isoform 4
- pyruvate dehydrogenase kinase, isoenzyme 4
- pyruvate dehydrogenase kinase, isozyme 4
- pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial
Background
PDK4 is a mitochondrial protein with a histidine kinase domain that is a member of the PDK/BCKDK protein kinase family. This protein is located in the matrix of the mitrochondria and its expression is regulated by glucocorticoids, retinoic acid and insulin. PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.