PDGF R beta Antibody Summary
| Immunogen |
This antibody is specific for the N Terminus Region of the target protein.
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| Specificity |
This product is specific for Human PDGFRB.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
PDGFRB
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA, Western Blot and Immunohistochemistry-Paraffin.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for PDGF R beta Antibody
- beta-type platelet-derived growth factor receptor
- CD140 antigen-like family member B
- CD140b antigen
- CD140b
- EC 2.7.10
- EC 2.7.10.1
- JTK12
- PDGF R beta
- PDGFR
- PDGFR1
- PDGFRB
- PDGF-R-beta
- platelet-derived growth factor receptor, beta polypeptide
Background
Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.