PDE6G Antibody (2F5)

Product: CY6-YNE

PDE6G Antibody (2F5) Summary

Immunogen
Full length human recombinant protein of human PDE6G(NP_002593) produced in HEK293T cell.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PDE6G
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PDE6G Antibody (2F5)

  • DKFZp686C0587
  • GMP-PDE gamma
  • MGC125749
  • PDEG
  • phosphodiesterase 6G, cGMP-specific, rod, gamma
  • retinal rod rhodopsin-sensitive cGMP 3-5-cyclic phosphodiesterase subunit gamma
  • rod cG-PDE G
  • RP57

Background

This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

PMID: 11224180