PDE6D Antibody (5C7) Summary
| Immunogen |
PDE6D (AAH07831, 1 a.a. – 150 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
|
| Localization |
Cytoplasmic
|
| Specificity |
PDE6D – phosphodiesterase 6D, cGMP-specific, rod, delta
|
| Isotype |
IgG2b Kappa
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PDE6D
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PDE6D Antibody (5C7)
- GMP-PDE delta
- PDED
- phosphodiesterase 6D, cGMP-specific, rod, delta
- Protein p17
- retinal rod rhodopsin-sensitive cGMP 3-5-cyclic phosphodiesterase subunitdelta
Background
Human PDE6D was originally identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. Catalytically active PDE6 is a heterodimer (alpha/beta) that is regulated by two inhibitory y subunits. As PDE6D does not modify the catalytic properties of PDEalpha/beta, its function is still unresolved. Recombinant human PDE6D, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.