Product: Mutagenic Impurity of Tenofovir Disoproxil
PDE5A Antibody (9H5) Summary
| Immunogen |
PDE5A (NP_001074, 29 a.a. – 138 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKEGIRGHTESCSCPLQQSPRADNSVPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEKKEQMPLTP
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| Specificity |
PDE5A – phosphodiesterase 5A, cGMP-specific
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| Isotype |
IgG3 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
PDE5A
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PDE5A Antibody (9H5)
- CGB-PDE
- cGMP-binding cGMP-specific 3-5-cyclic nucleotide phosphodiesterase
- cGMP-binding cGMP-specific phosphodiesterase
- cGMP-specific 3-5-cyclic phosphodiesterase
- cGMP-specific phosphodiesterase type 5A
- CN5A
- EC 3.1.4
- EC 3.1.4.35
- PDE5
- phosphodiesterase 5A, cGMP-specific
- phosphodiesterase isozyme 5
Background
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.