PDE11A Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human PDE11A. The exact sequence is proprietary.
|
| Localization |
Cytoplasm, cytosol
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PDE11A
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PDE11A Antibody
- cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
- cAMP and cGMP phosphodiesterase 11A
- cyclic nucleotide phosphodiesterase 11A
- dual 3-5-cyclic-AMP and -GMP phosphodiesterase 11A
- EC 3.1.4
- EC 3.1.4.17
- EC 3.1.4.35
- FLJ23693
- MGC133355
- MGC133356
- PDE11A1
- PDE11A2
- PDE11A3
- phosphodiesterase 11A
- PPNAD2
Background
The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.