PALS1/MPP5 Antibody

Product: Tacalcitol (monohydrate)

PALS1/MPP5 Antibody Summary

Immunogen
Peptide with sequence NKASPPFPLISNAQ-C corresponding to N-Terminus according to NP_071919.1.
Clonality
Polyclonal
Host
Goat
Gene
MPP5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1 – 3 ug/ml
  • Immunohistochemistry 1:10 – 1:500
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 75 kDa band observed in human brain lysate (calculated MW of 77.3 kDa band according to NP_071919).
Publications
Read Publication using NB300-952.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Canine, Porcine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PALS1/MPP5 Antibody

  • MAGUK p55 subfamily member 5
  • membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
  • MPP5
  • PALS1
  • PALS1FLJ12615
  • Stardust

Background

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001). MPP5 is a member of the p55-like MAGUK subfamily.

PMID: 25266676