PAC1R Antibody

Product: Sotetsuflavone

PAC1R Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from C-terminus of human ADCYAP1R1.
Localization
Cell Membrane
Specificity
Human ADCYAP1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Fish (94%), Zebrafish (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
ADCYAP1R1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 15 ug/ml

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Panda (100%), Lizard (100%), Stickleback (94%), Pufferfish (94%0, Mouse (88%), Rat (88%), Hamster (88%), Elephant (88%), Bovine (88%), Equine (88%), Porcine (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAC1R Antibody

  • ADCYAP1R1
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
  • PAC1R
  • PACAP type I receptor
  • PACAPR
  • PACAP-R1
  • PACAP-R-1
  • PACAPRI
  • PACAPRPAC1
  • pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
  • pituitary adenylate cyclase-activating polypeptide type I receptor

Background

The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.

PMID: 12163113

PAC1R Antibody

Product: Nile Red

PAC1R Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: SDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWD
Specificity
Specificity of antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADCYAP1R1
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

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Applications/Dilutions

Dilutions
  • Western Blot 1:100 – 1:250
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:20 – 1:50
Application Notes
For IHC-Paraffin HIER pH6 retrieval is recommended.
Control Peptide
PAC1R Protein (NBP2-47340PEP)

Reactivity Notes

Expected species cross reactivity based on sequence homology: Mouse (89%), Rat (89%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PAC1R Antibody

  • ADCYAP1R1
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
  • PAC1R
  • PACAP type I receptor
  • PACAPR
  • PACAP-R1
  • PACAP-R-1
  • PACAPRI
  • PACAPRPAC1
  • pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
  • pituitary adenylate cyclase-activating polypeptide type I receptor

PMID: 23233668