P2Y1/P2RY1 Antibody Summary
| Immunogen |
Synthetic 19 amino acid peptide from C-terminus of human P2RY1 / P2Y1.
|
| Localization |
Plasma membrane
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| Specificity |
Human P2RY1 / P2Y1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
|
| Predicted Species |
Xenopus (95%), Opossum (100%), Chicken (95%), Turkey (95%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
P2RY1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (95%), Platypus (95%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for P2Y1/P2RY1 Antibody
- ATP receptor
- P2 purinoceptor subtype Y1
- P2RY1
- P2Y purinoceptor 1
- P2Y1
- P2Y1platelet ADP receptor
- purinergic receptor P2Y, G-protein coupled, 1
- Purinergic receptor
Background
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.