Otubain-1 Antibody (1C12) Summary
| Immunogen |
OTUB1 (AAH07519, 1 a.a. ~ 272 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHIFPEGSEP
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| Specificity |
OTUB1 – OTU domain, ubiquitin aldehyde binding 1 (1C12)
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
OTUB1
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against cell lysate for western blot. It has also been used for ELISA.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Otubain-1 Antibody (1C12)
- Deubiquitinating enzyme OTUB1
- EC 3.1.2
- EC 3.4.19.12
- FLJ20113
- FLJ40710
- hOTU1
- MGC111158
- OTB1
- OTB1MGC4584
- OTU domain, ubiquitin aldehyde binding 1
- OTU domain-containing ubiquitin aldehyde-binding protein 1
- OTU1
- OTU1OTU-domain Ubal-binding 1
- OTUB1
- Otubain1
- Otubain-1
- ubiquitin thioesterase OTUB1
- ubiquitin-specific protease otubain 1
- Ubiquitin-specific-processing protease OTUB1
Background
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]