OXTR Antibody Summary
| Immunogen |
A 20 amino acid synthetic peptide within the N-terminal extracellular domain of human Oxytocin Receptor.
|
| Specificity |
Human Oxytocin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DOK3 (50%).
|
| Predicted Species |
Mouse (95%), Rat (90%), Porcine (90%), Primate (100%), Monkey (95%), Bovine (90%), Sheep (90%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
OXTR
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Elephant (95%), Panda (90%), Bat (85%), Canine (85%), Marmoset (80%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS and 2% Sucrose
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
0.84 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for OXTR Antibody
- OT-R
- OXTR
- oxytocin receptor
Background
The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.