Product: Chelerythrine Chloride
Nova1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the C-terminus region of human NOVA1. The exact sequence is proprietary.
|
| Localization |
Nucleus
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| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
NOVA1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Expected cross reactivity based on sequence homology: Xenopus laevis (95%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.92 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Nova1 Antibody
- neuro-oncological ventral antigen 1Nova-1
- Onconeural ventral antigen 1
- Paraneoplastic Ri antigen
- RNA-binding protein Nova-1
- Ventral neuron-specific protein 1
Background
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.