Niemann-Pick C1 Antibody (4H2) Summary
| Immunogen |
NPC1 (AAH63302, 151 a.a. – 250 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPK
|
| Localization |
Late endosome and Lysosome membrane; Single-pass membrane protein.
|
| Specificity |
NPC1 – Niemann-Pick disease, type C1
|
| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
NPC1
|
| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Niemann-Pick C1 Antibody (4H2)
- FLJ98532
- Niemann-Pick C1 protein
- Niemann-Pick disease, type C1
- NPC
- NPC1
Background
This gene was identified as the gene that when mutated, results in Niemann-Pick C disease. The encoded protein is a putative integral membrane protein that contains motifs consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations.