Neurobeachin Antibody Summary
| Immunogen |
Peptide with sequence C-DFNRWHYEHQNRY corresponding to C-Terminus according to NP_056493.3, NP_001191126.1.
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| Epitope |
DFNRWHYEHQNRY
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| Specificity |
This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1).
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
NBEA
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 300 kDa band observed in lysates of transfected HEK293 and endogenously in lysates of insulinoma cell line B-TC3 (calculated MW of 327 kDa band according to NP_056493.3), provided by Professor John Creemers, K.U. Leuven, Belgium. Data obtained from a previous batch (different goat). IHC-P: Human cerebral cortex shows textured cytoplasm staining in the neuronal cell bodies.
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Canine, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Neurobeachin Antibody
- BCL8Blysosomal trafficking regulator 2
- EC 1.14.14.5
- EC 6.1.1.11
- FLJ10197
- KIAA1544
- Lysosomal-trafficking regulator 2
- LYST2
- neurobeachin
- Protein BCL8B
Background
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins.