NM23-H1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human nm23-H1. The exact sequence is proprietary.
|
| Localization |
Cytoplasm; Nucleus
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
NME1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Chimpanzee (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for NM23-H1 Antibody
- EC 2.7.4.6
- GAAD
- Granzyme A-activated DNase
- Metastasis inhibition factor nm23
- NB
- NBS
- NDK A
- NDKA
- NDP kinase A
- NDPKA
- NDPK-A
- NM23A
- NM23AWD
- NM23H1
- NM23-H1
- NME1
- non-metastatic cells 1, protein (NM23A) expressed in
- nucleoside diphosphate kinase A
- Tumor metastatic process-associated protein
Background
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq]