NGF R/TNFRSF16/p75NTR Antibody (NTR/912) [Alexa Fluor® 700] Summary
| Immunogen |
Recombinant human p75 NGFR protein
|
| Localization |
Cell surface and cytoplasmic
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| Marker |
Soft Tissue Tumor Marker
|
| Specificity |
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NGFR
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Alternate Names for NGF R/TNFRSF16/p75NTR Antibody (NTR/912) [Alexa Fluor® 700]
- CD271 antigen
- CD271
- Gp80-LNGFR
- member 16
- nerve growth factor receptor
- NGF R
- NGF receptor
- NGFR
- p75 ICD
- p75 NTR
- TNFRSF16
- TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16)
- tumor necrosis factor receptor superfamily member 16