NGF R/TNFRSF16/p75NTR Antibody (NGFR5 + NTR/912) [DyLight 755]

Product: Butenafine (Hydrochloride)

NGF R/TNFRSF16/p75NTR Antibody (NGFR5 NTR/912) [DyLight 755] Summary

Immunogen
NGFR from A875 melanoma cells (NGFR5); Recombinant human p75 NGFR protein (NTR/912)
Localization
Cell surface and cytoplasmic
Marker
Soft Tissue Tumor Marker
Specificity
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
NGFR
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for NGF R/TNFRSF16/p75NTR Antibody (NGFR5 NTR/912) [DyLight 755]

  • CD271 antigen
  • CD271
  • Gp80-LNGFR
  • member 16
  • nerve growth factor receptor
  • NGF R
  • NGF receptor
  • NGFR
  • p75 ICD
  • p75 NTR
  • TNFRSF16
  • TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16)
  • tumor necrosis factor receptor superfamily member 16

PMID: 24985044