NEK3 Antibody (2F8)

Product: Vandetanib

NEK3 Antibody (2F8) Summary

Immunogen
NEK3 (AAH19916 406 a.a. – 506 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QWLKETPDTLLNILKNADLSLAFQTYTIYRPGSEGFLKGPLSEETEASDSVDGGHDSVILDPERLEPGLDEEDTDFEEEDDNPDWVSELKKRAGWQGLCDR
Specificity
NEK3 – NIMA (never in mitosis gene a)-related kinase 3
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NEK3
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IF and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NEK3 Antibody (2F8)

  • EC 2.7.11
  • EC 2.7.11.1
  • glycogen synthase A kinase
  • HSPK 36
  • HSPK36
  • hydroxyalkyl-protein kinase
  • MGC29949
  • Never in mitosis A-related kinase 3
  • NIMA (never in mitosis gene a)-related kinase 3
  • NimA-related protein kinase 3
  • phosphorylase B kinase kinase
  • serine/threonine-protein kinase Nek3

Background

In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. The protein encoded by this gene is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. Three transcript variants have been found for this gene, but the full-length nature of only two of them has been characterized.

PMID: 9449278