NEIL2 Antibody (1B7)

Product: SB 203581

NEIL2 Antibody (1B7) Summary

Immunogen
NEIL2 (AAH13964, 1 a.a. ~ 333 a.a) full length recombinant protein with GST tag.MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDEEMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLERDAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNCQLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYRAGIHPLSLGSVLSAS
Specificity
NEIL2 – nei like 2 (E. coli)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NEIL2
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against transfected lysate and recombinant protein for western blot. It has also been used for RNAi validation and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NEIL2 Antibody (1B7)

  • DNA glycosylase/AP lyase Neil2
  • EC 3.2.2.-
  • EC 4.2.99.18
  • endonuclease 8-like 2
  • Endonuclease VIII-like 2
  • FLJ31644
  • MGC2832
  • MGC4505
  • NEH2DNA-(apurinic or apyrimidinic site) lyase Neil2
  • nei endonuclease VIII-like 2 (E. coli)
  • Nei homolog 2
  • nei like 2 (E. coli)
  • nei like 2
  • NEI2
  • Nei-like protein 2

Background

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM]

PMID: 18650397