NEIL2 Antibody (1B7) Summary
| Immunogen |
NEIL2 (AAH13964, 1 a.a. ~ 333 a.a) full length recombinant protein with GST tag.MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDEEMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLERDAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNCQLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYRAGIHPLSLGSVLSAS
|
| Specificity |
NEIL2 – nei like 2 (E. coli)
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NEIL2
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against transfected lysate and recombinant protein for western blot. It has also been used for RNAi validation and ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for NEIL2 Antibody (1B7)
- DNA glycosylase/AP lyase Neil2
- EC 3.2.2.-
- EC 4.2.99.18
- endonuclease 8-like 2
- Endonuclease VIII-like 2
- FLJ31644
- MGC2832
- MGC4505
- NEH2DNA-(apurinic or apyrimidinic site) lyase Neil2
- nei endonuclease VIII-like 2 (E. coli)
- Nei homolog 2
- nei like 2 (E. coli)
- nei like 2
- NEI2
- Nei-like protein 2
Background
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM]