NCKIPSD Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 672 and 722 of human SH3 protein interacting with Nck, 90 kDa using the numbering given in entry NP_057537.1 (GeneID 51517).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
NCKIPSD
|
| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
0.2 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for NCKIPSD Antibody
- 54 kDa vimentin-interacting protein
- 90 kDa SH3 protein interacting with Nck
- AF3p21
- AF3P21DIP-1
- dia interacting protein
- Dia-interacting protein 1
- diaphanous protein interacting protein
- Diaphanous protein-interacting protein
- DIP
- DIP1
- MGC23891
- NCK interacting protein with SH3 domain
- ORF1
- SPIN90VIP54
- WASLBP
- WASP-interacting SH3-domain protein
- WISHSH3 adapter protein SPIN90
- Wisk90 kDa
Background
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.