Product: Cefotaxime (sodium salt)
NCCRP1 Antibody (5C.6) Summary
| Immunogen |
Purified NCC cells from catfish.
|
| Specificity |
Nonspecific Cytotoxic Cell (5C.6)
|
| Isotype |
IgM
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NCCRP1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Tilapia and Catfish.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
and 1 mg/ml BSA
|
| Preservative |
0.05% Sodium Azide
|
| Concentration |
0.73 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for NCCRP1 Antibody (5C.6)
- LOC342897
- NCCRP-1
- non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
- nonspecific cytotoxic cell receptor protein 1 homolog
- non-specific cytotoxic cell receptor protein 1 homolog
Background
Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals.