Product: (R)-Rivastigmine (D8 tartrate)
NCAM-1/CD56 Antibody (MEM 188) [Allophycocyanin] Summary
| Immunogen |
Acute myelogenous leukemia cell line KG-1
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| Specificity |
Human CD56
|
| Isotype |
IgG2a
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NCAM1
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
Additional applications reported in literature include Immunoprecipitation, Western blot, and Immunohistochemistry.
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| Positive Control |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
PBS and 0.2% (w/v) high grade BSA (protease free)
|
| Preservative |
15mM Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for NCAM-1/CD56 Antibody (MEM 188) [Allophycocyanin]
- CD56 / NCAM-1
- CD56 antigen
- CD56
- MSK39
- NCAM1
- N-CAM-1
- NCAM-1
- NCAMantigen recognized by monoclonal 5.1H11
- neural cell adhesion molecule 1
- neural cell adhesion molecule, NCAM
Background
CD56 + NCAM-1 Antibody (MEM-188) [Allophycocyanin] is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.