NCAM-1/CD56 Antibody (MEM 188) Summary
| Immunogen |
Acute myelogenous leukemia cell line KG-1
|
| Specificity |
Human CD56
|
| Isotype |
IgG2a
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
NCAM1
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
0.1M BBS (pH 8.2)
|
| Preservative |
No Preservative
|
| Concentration |
0.1 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for NCAM-1/CD56 Antibody (MEM 188)
- CD56 / NCAM-1
- CD56 antigen
- CD56
- MSK39
- NCAM1
- N-CAM-1
- NCAM-1
- NCAMantigen recognized by monoclonal 5.1H11
- neural cell adhesion molecule 1
- neural cell adhesion molecule, NCAM
Background
CD56, an isoform of the neural cell adhesion molecule (NCAM), is a 220 kDa heavily glycosylated type I transmembrane protein. On human hematopoietic cells, its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial. (1-4)