Myosin 1C Antibody

Product: BMS-599626

Myosin 1C Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human Myosin 1C. The exact sequence is proprietary.
Localization
Cytoplasm; Cell membrane (By similarity); Cell projection; stereocilium membrane (By similarity); Isoform 3: Nucleus; nucleoplasm; Nucleus; nucleolus; nuclear pore complex
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MYO1C
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • Immunohistochemistry 10 – 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
118 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Myosin 1C Antibody

  • FLJ23903
  • MMIb
  • MMI-beta
  • Myosin I beta
  • myosin IC
  • myosin-I beta
  • myosin-Ic
  • myr2
  • NMI
  • nuclear myosin I

Background

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq]

PMID: 23285225