Myoglobin Antibody Summary
| Specificity |
This antibody reacts with cardiac and skeletal forms of myoglobin.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
MB
|
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|
Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Store the unopened product at 2 – 8° C.
|
| Buffer |
10 mM sodium phosphate, 0.85% (w/v) sodium chloride, pH 7.2 (PBS) with 5% trehalose
|
| Preservative |
No Preservative
|
| Reconstitution Instructions |
Sterile PBS to a final concentration of 0.2 mg/mL.
|
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Myoglobin Antibody
- MB
- MGC13548
- Myoglobin
- PVALB
Background
Myoglobin is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. Its name derives from its structural and functional similarity to hemoglobin, the oxygen binding protein found in red blood cells. Functions of myoglobin include oxygen storage and transport, as well as scavenging of NO and reactive oxygen species. Myoglobin also serves as a sensitive marker for muscle injury resulting from cardiac infarction. Surprisingly, mice in which myoglobin has been removed by gene targeting are able to perform extensive exercise and respond normally to hypoxic challenge.