Migfilin Antibody (5E11) Summary
| Immunogen |
FBLIM1 (NP_060026, 270 a.a. ~ 374 a.a) partial recombinant protein with GST tag.VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
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| Specificity |
FBLIM1 – filamin binding LIM protein 1
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
FBLIM1
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactive against cell lysate, transfected lysate and recombinant protein for western blot. It has also been used for ELISA.
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| Publications |
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Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Migfilin Antibody (5E11)
- CAL
- DKFZp434G171
- FBLP-1FBLP1CSX-associated LIM
- filamin binding LIM protein 1
- filamin-binding LIM protein 1
- filamin-binding LIM protein-1
- MIG2-interacting protein
- migfilin
- mitogen-inducible 2 interacting protein
- Mitogen-inducible 2-interacting protein
Background
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.