Meprin alpha Subunit/MEP1A Antibody

Product: SPACE peptide

Meprin alpha Subunit/MEP1A Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Meprin alpha. The exact sequence is proprietary.
Localization
Membrane, Single-pass type I membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MEP1A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Paraffin
Application Notes
IHC-P and ICC/IF usages usage reported in scientific literature (PMID: 23427141).
Theoretical MW
84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP1-32595 in the following applications:

  • ICC/IF
    1 publication
  • IHC-P
    1 publication

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23427141). Rat (85%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Meprin alpha Subunit/MEP1A Antibody

  • bA268F1.1 (meprin A alpha (PABA peptide hydrolase))
  • EC 3.4.24
  • EC 3.4.24.18
  • endopeptidase-2
  • MEP1A
  • meprin A subunit alpha
  • meprin A, alpha (PABA peptide hydrolase)
  • Meprin alpha Subunit
  • N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha
  • PABA peptide hydrolase
  • PPH alpha
  • PPHA

Background

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

PMID: 7752204